1-Bromo-2-methoxy-3-nitro-benzene o loʻo faʻaaogaina e avea ma mea vavalalata o Eltrombopag .
Eltrombopag, atiina ae e GlaxoSmithKline (GSK) i Peretania ma mulimuli ane atiina ae soofaatasi ma Novartis i Suitiselani, o le muamua ma e naʻo le faʻatagaina laiti mole non peptide TPO receptor agonist i le lalolagi.Eltrombopag na faʻamaonia e le US FDA i le 2008 mo le togafitiga o le idiopathic thrombocytopenic purpura (ITP), ma i le 2014 mo togafitiga o le maʻi aplastic anemia (AA).O le vailaʻau muamua foʻi na faʻamaonia e le US FDA mo togafitiga o le AA i le 30 tausaga talu ai nei.
I le december2012, ua faamaonia e le US FDA Eltrombopag mo le togafitiga o thrombocytopenia i tagata mamaʻi ma hepatitis C (CHC), ina ia hepatitis C maʻi ma le le lelei prognosis ona o le maualalo platelet faitau e mafai ona amata ma tausia interferon faavae togafitiga tulaga mo maʻi ate.I le Fepuari3, 2014, GlaxoSmithKline na faʻasalalau e le FDA na tuʻuina atu le agavaa o vailaʻau faʻapitoa mo togafitiga o Eltrombopag mo togafitiga o le hemopenia i tagata mamaʻi e maua i le chemicalbook aplastic anemia (SAA) e leʻi tali atoatoa i le immunotherapy.I le aso 24 o Aokuso, 2015, na faʻamaonia ai e le US FDA Eltrombopag mo togafitiga o le thrombocytopenia i tagata matutua ma tamaiti e taʻi 1 tausaga ma sili atu ma le thrombocytopenia puipuia tumau (ITP) e le lava le tali atu i corticosteroids, immunoglobulins poʻo splenectomy.I le Ianuari 4, 2018, na faʻamaonia ai Eltrombopag e lisiina i Saina mo togafitiga o le thrombocytopenia puipuia muamua (ITP).
JIN DUN Medical uaFa'ailoga ISO ma fa'amalieina tulaga fa'atupu GMP, fa'afaigaluegaina tagata tomai faapitoa i le fa'aogaina o vaila'au i totonu ma fafo ma le poto masani e ta'ita'ia le R&D a le kamupani.
FA'ATAITAI O GALUEGA
●Mata'u maualuga Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Toe Fa'atonuga
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Meafaigaluega
O loʻo i ai i la matou Fale suʻesuʻe mea faʻapitoa ma suʻega, e pei o le: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
Vaega su'esu'e
Jindun Medical ei ai se vaega o tagata faigaluega R & D faʻapolofesa, ma faʻafaigaluegaina le tele o tagata tomai faʻapitoa mo vailaʻau faʻapitoa i totonu ma fafo e taʻitaʻia le R&D, ma faʻafaigofie atili ma lelei a tatou faʻasologa.
Ua matou fesoasoani i nisi o kamupani pito i luga ole fale talavai, pei oleHansoh, Hengrui ma HEC Pharm.O iinei o le a tatou faaali atu ai se vaega o latou.
Fa'asinomaga Tulaga Muamua:
Kase Numera: 110351-94-5
Tulaga Fa'apitoa Lua:
Cas Nu.: 144848-24-8
Tulaga Fa'apitoa Tolu:
Cas Nu.: 200636-54-0
1.Fa'asinomaga Fou Intermediates po'o API.E tutusa ma le faʻasoaina o mataupu i luga, o loʻo i ai i tagata faʻatau manaʻoga mo Intermediates patino poʻo API, ma e le mafai ona latou mauaina oloa manaʻomia i le maketi, ona mafai lea ona matou fesoasoani i le Customize.
2.Fa'atonuga Fa'agasologa mo Oloa Tuai.O la matou 'au o le a fesoasoani i le fa'aleleia ma le fa'aleleia o ia gaosiga o lo'o tuai ai le auala e tali mai ai, e maualuga le tau o gaosiga, ma e maualalo le lelei.E mafai ona matou tuʻuina atu faʻamaumauga atoa mo le faʻaaogaina o tekonolosi ma le faʻaleleia atili o le faagasologa, fesoasoani i tagata faʻatau mo se gaosiga sili atu.
Mai fuala'au fa'atatau ile INDs, JIN DUN Medical e tu'uina atu ia te oefofo R&D fa'apitoa e tasi taofi.
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