5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-tasi

5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-o loʻo faʻaaogaina e avea ma mea vavalalata o Prasugrel .
O le Prasugrel o se thiophenopyridine antiplatelet na fausia e Eli Lilly ma daiichisankyo, o se fale gaosi oloa Iapani.O se vailaau muamua.E fausia ai se mole malosi pe a maeʻa le metabolism e ala i le cytochrome P450 i le ate ma tuʻufaʻatasia ma le platelet P2Y12 receptor e faʻamalosi malosi e faasaga i platelet aggregation.O suʻesuʻega faʻapitoa ua faʻamaonia ai o le 60 mg dose e sili atu le aʻafiaga o le anticoagulant nai lo le 300 mg standard dose ma le 600 mg faʻateleina le fua o le clopidogrel, lea e mafai ona faʻaitiitia ai le lamatiaga atoatoa o le fatu fatu, stroke ma le oti ona o le fatu fatu e 20%, ma e vave ona aʻafia. , a'afiaga fa'amalolo lelei, fa'ato'aga lelei o vaila'au ma le bioavailability, ma maualalo le o'ona.