Lelei lelei 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9

E le gata o le a matou taumafai malosi e ofoina atu kamupani sili ona lelei i le toetoe lava o tagata faʻatau uma, ae ua sauni foi e talia soʻo se fautuaga e ofoina mai e le au faʻatau mo le lelei 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, O le 'au a la matou kamupani faʻatasi ma le faʻaogaina o tekinolosi faʻaonaponei e tuʻuina atu oloa lelei atoatoa e sili ona faʻaaloalo ma talisapaia e o tatou faʻamoemoe i le lalolagi atoa.
E le gata o le a matou taumafai i le mea sili matou te ofoina atu kamupani sili ona lelei i le toetoe o tagata faʻatau uma, ae ua sauni foi e talia soʻo se fautuaga e ofoina mai e a matou tagata faʻatau moSaina 2-Cyanobenzyl Bromide Powder ma Alpha-Bromo-O-Toluonitrile, Matou te talitonu malosi o tekinolosi ma auaunaga o lo matou faʻavae i aso nei ma o le lelei o le a fausia ai a matou puipui faʻalagolago i le lumanaʻi.Na'o matou e sili atu ma sili atu le lelei, e mafai ona matou ausia a matou tagata fa'atau ma i matou foi.Faʻafeiloaʻi tagata faʻatau i luga o le upu e faʻafesoʻotaʻi i matou mo le mauaina atili o pisinisi ma mafutaga faʻalagolago.Matou te i ai pea iinei e galulue mo ou manaʻoga i soʻo se taimi e te manaʻomia ai.

Fa'aaogā:Intermediate mo Linagliptin.

Fa'aoga:Intermediate mo Linagliptin
Tulaga Fa'atonu:tulaga tau pisinisi
Su'ega:98-102%

fafo:Pa'epa'e i le pa'epa'e samasama
afifi:25kg/papa

Le suʻesuʻeina o le linagliptin o loʻo i ai nei ma lona 8-bromo-7-(2-butynyl) -3,7-dihydro-3-methyl-1- [(4-methyl -2-quinazolinyl) methyl) -1H-purine- 2,6-dione (11) auala faʻapipiʻi, saili se auala faʻapipiʻi talafeagai mo le gaosiga o fale gaosi oloa.Metotia: fai se aotelega o auala fa'apipi'i eseese.I'uga ma fa'ai'uga: Auala 2.2 o lo'o i ai se faiga faigofie ma maualalo le tau, lea e sili atu ona talafeagai mo le gaosiga o fale gaosi oloa.

8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione o se vaega autu i le tuʻufaʻatasia o le hypoglycemic drug linagliptin.O le faʻaogaina o le 1 faʻaaogaina le methyl urea ma le cyanoacetic acid e avea ma mea amata, ma faʻaalia ni laasaga e ono o le condensation, cyclization, nitrosation, faʻaitiitia, cyclization, ma le bromine ma le aofaʻi atoa o le 46.3%.O faʻatulagaga o fesoʻotaʻiga uma na faʻamaonia e le 1HNMR.

O le mea fou fou e fesoʻotaʻi ma se auala faigofie sauniuni o le linagliptin maualuga-mama.Quinazoline, o le mea autu autu mo le sauniuniga o le linagliptin 8 bromo 7 (2 butyne 1 base) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, o le intermediate e vavaeeseina. filtration, ona tali atu lea i le (R)3 aminopiperidine dihydrochloride e maua ai se vaifofo e iai le linagliptin.A maeʻa ona toe gaosia le vaifofo o loʻo iai le linagliptin, Deliraliptin oloa mama.O le sauniuniga o le autu autu o le mea fou fou e faʻaaogaina ai se auala e tasi-pot, lea e faigofie ona faʻaogaina ma faʻaleleia le fua.A maeʻa ona tuʻueseese le vaega autu, e tali atu i le (R)3 aminopiperidine dihydrochloride, ma o le mauaina o le linagliptin mama maualuga e fetaui ma le gaosiga ma le taʻutinoga manaʻomia a kamupani vailaʻau i le tele.

E le gata o le a matou taumafai malosi e ofoina atu kamupani sili ona lelei i le toetoe lava o tagata faʻatau uma, ae ua sauni foi e talia soʻo se fautuaga e ofoina mai e le au faʻatau mo le lelei 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, O le 'au a la matou kamupani faʻatasi ma le faʻaogaina o tekinolosi faʻaonaponei e tuʻuina atu oloa lelei atoatoa e sili ona faʻaaloalo ma talisapaia e o tatou faʻamoemoe i le lalolagi atoa.
Lelei leleiSaina 2-Cyanobenzyl Bromide Powder ma Alpha-Bromo-O-Toluonitrile, Matou te talitonu malosi o tekinolosi ma auaunaga o lo matou faʻavae i aso nei ma o le lelei o le a fausia ai a matou puipui faʻalagolago i le lumanaʻi.Na'o matou e sili atu ma sili atu le lelei, e mafai ona matou ausia a matou tagata fa'atau ma i matou foi.Faʻafeiloaʻi tagata faʻatau i luga o le upu e faʻafesoʻotaʻi i matou mo le mauaina atili o pisinisi ma mafutaga faʻalagolago.Matou te i ai pea iinei e galulue mo ou manaʻoga i soʻo se taimi e te manaʻomia ai.