Guanosine
Guanosine
Guanosine o loʻo faʻaaogaina e fai ma vaeluaga ole Valaciclovir.
Valacyclovir o se guanine analog antiviral vailaʻau.O lo'o fa'aaogaina i le togafitiga o le herpes simplex ma le herpes zoster infection i fa'ama'i fa'afeusuaiga.O lenei oloa o le mea muamua lea o le acyclovir.E vave ona mitiia pe a uma le tuʻu gutu ma vave ona liua i le acyclovir i le tino.O lona aafiaga antiviral e taʻalo e le acyclovir.A uma ona ulufale le acyclovir i sela ua aafia i le herpes, e tauva ma le deoxynucleoside mo le virus thymidine deoxynucleoside kinase poʻo cell kinase, ma o le vailaʻau e phosphorylated i le activated acyclic guanosine triphosphate.I le avea ai ma sui o le toe faia o siama, o le acyclovir e tauva ma le deoxyguanine triphosphate mo le DNA polymerase virus, lea e taofia ai le DNA synthesis ma faʻaalia ai le antiviral.O le antiviral gaioiga o lenei oloa i vivo e sili atu nai lo le acyclovir, ma o le faasinomaga o togafitiga o le herpes simplex virus type I ma le ituaiga II e 42.91% ma le 30.13% maualuga atu nai lo le acyclovir.E maualuga fo'i lona a'afiaga i le fa'ama'i varicella zoster.
JIN DUN Medical uaFa'ailoga ISO ma fa'amalieina tulaga fa'atupu GMP, fa'afaigaluegaina tagata tomai faapitoa i le fa'aogaina o vaila'au i totonu ma fafo ma le poto masani e ta'ita'ia le R&D a le kamupani.
FA'ATAITAI O GALUEGA
●Mata'u maualuga Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Toe Fa'atonuga
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Meafaigaluega
O loʻo i ai i la matou Fale suʻesuʻe mea faʻapitoa ma suʻega, e pei o le: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
Vaega su'esu'e
Jindun Medical ei ai se vaega o tagata faigaluega R & D faʻapolofesa, ma faʻafaigaluegaina le tele o tagata tomai faʻapitoa mo vailaʻau faʻapitoa i totonu ma fafo e taʻitaʻia le R&D, ma faʻafaigofie atili ma lelei a tatou faʻasologa.
Ua matou fesoasoani i nisi o kamupani pito i luga ole fale talavai, pei oleHansoh, Hengrui ma HEC Pharm.O iinei o le a tatou faaali atu ai se vaega o latou.
Fa'asinomaga Tulaga Muamua:
Kase Numera: 110351-94-5
Tulaga Fa'apitoa Lua:
Cas Nu.: 144848-24-8
Tulaga Fa'apitoa Tolu:
Cas Nu.: 200636-54-0
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