Lisi o tau mo le High Quality Antiviral Entecavir Powder CAS 142217-69-4 ma le tau sili ona lelei

Matou te tuʻuina atu foʻi kamupani faʻatau oloa poʻo auaunaga ma kamupani faʻamalosia vaalele.E iai a matou lava fale gaosimea ma ofisa su'esu'e.E mafai ona faigofie ona matou tuʻuina atu ia te oe toetoe lava o ituaiga uma o oloa e tutusa ma a matou oloa eseese mo PriceList mo le High Quality Antiviral Entecavir Powder CAS 142217-69-4 ma le Tau Sili, O le a matou taumafai pea e faʻateleina la matou kamupani ma tuʻuina atu oloa sili ona lelei. fa'atasi ai ma tau fa'atauva'a.So'o se su'esu'ega po'o se fa'amatalaga e matua fa'afetaia.Manatua e pu'e fua mai ia i matou.
Matou te tuʻuina atu foʻi kamupani faʻatau oloa poʻo auaunaga ma kamupani faʻamalosia vaalele.E iai a matou lava fale gaosimea ma ofisa su'esu'e.E faigofie ona matou tu'uina atu ia te oe toetoe o ituaiga uma o oloa e tutusa ma a matou oloa eseese moSaina Entecavir ma 142217-69-4, Matou te faʻafeiloaʻi ma le fiafia tagata faʻatau i totonu ma fafo e asiasi i la matou kamupani ma fai se talanoaga faʻapisinisi.O la matou kamupani e faʻamalosia pea le mataupu faavae o le "lelei lelei, tau talafeagai, le auaunaga muamua-vasega".Matou te naunau e fausia se taimi umi, faauo ma felagolagomai faʻatasi ma oe.

Entecavir（SQ 34676;BMS 200475）o le HBV Inhibitor filifilia ma aoga.I sela HepG2 EC50 tau o le 3.75 nM.O vaila'au fa'ato'a fa'ato'a fou e fa'ama'i-hepatitis B ma fa'ama'i-AIDS.

Entecavir aafiaga

O lenei oloa o le guanine nucleoside analog, lea e iai sona aafiaga fa'alavelave ile siama ole hepatitis B (HBV) polymerase.E mafai ona phosphorylated i triphosphate malosi, ma o le afa-ola o le triphosphate i le sela e 15 itula.E ala i le tauva ma le HBV polymerase's natural substrate deoxyguanosine triphosphate, e mafai e le entecavir triphosphate ona taofia gaoioiga uma e tolu a viral polymerase (reverse transcriptase): (1) HBV polymerase initiation;(2) pregenomic mRNA Le fa'avaeina o le fa'asologa o le fa'asologa fa'asolosolo;(3) Le tu'ufa'atasiga o le manoa lelei o le HBV DNA.O le fa'alavelave fa'alavelave (Ki) ole entecavir triphosphate ile HBV DNA polymerase ole 0.0012μM.Entecavir triphosphate e vaivai le a'afiaga i le cell α, β, δ DNA polymerase ma le mitochondrial γ DNA polymerase, ma le Ki tau o le 18 i le 160 μM.

Fa'aletino ma kemisi o le Entecavir

Entecavir Customs

Fa'amatalaga fa'aopoopo:

Qu Qiang (PhD i falemaʻi falemaʻi, Matagaluega o Falemaʻi, Falemai Xiangya, Iunivesite i Saute Tutotonu) ma Wang Ruoguang (Fomaʻi Fomai, postdoctoral i le biology, Changsha Ruoguang Medical Research Center) na tusia foi e faapea: i le entecavir regimen, entecavir e mafai ona ave. mo ni nai tausaga po o le 10 tausaga.E sili atu nai lo tausaga.Ma e mafai ona faʻaaogaina e fafine maʻitaga, faʻaalia le saogalemu lelei.

Ile fa'amasinoina mai nei molecular pharmacological mechanisms, Entecavir e mafai ona i ai se fa'alavelave fa'ama'i lautele, e le gata ina aoga i le HBV.

E masani foi ona matou faʻaogaina le Entecavir e togafitia ai faʻamaʻi pipisi o le manava i totonu o le falemaʻi, ma e ofoofogia le aafiaga.

I le taimi nei, i se iloiloga lata mai o le silia ma le 500 COVID19 gasegase i Hubei (se nofoaga), naʻo le tasi le tagata na ave le entecavir.O le taimi o talavai o le amataga o Ianuari, ona taofi lea o le fualaau.

A o lagolagoina le aufaigaluega fomaʻi i Hubei, o nisi o fomaʻi, poʻo vaega e maualuga le lamatiaga, o loʻo faʻaogaina nei le Entecavir e puipuia ai le COVID19, e leai se faʻamaʻi pipisi.O tagata masalomia o loʻo ave le entecavir, e leai se tasi ua alualu i luma e maua i le COVID19.

mataupu pateni:

E masani ona lua faiga, 06 faagasologa ma 89 faagasologa.O le mutaaga o le pateni mo le 06 faagasologa ua vave tele (e muta i le 2023)!E ui lava o le tau o le faagasologa e maualalo, o le tulaga lelei e fai si lelei, ma e mafai e le aufaigaluega ona malosi, fautuaga a le tagata lava ia: Mo vailaʻau vailaʻau, faʻaoga le 06 faiga e aua le faʻamaualuga;mo kamupani vaila'au, 'aua ne'i fa'atauva'a ma 'aua ne'i fa'amata'u tele .

I le 2014, na ausia ai e Chia Tai Tianqing le faʻatauga faʻaletausaga o le 10 piliona yuan e ala i le faʻalagolago i vailaʻau faʻapitoa e pei o le entecavir, lea e entecavir e 20%.

Talu ai na faʻamaonia le entecavir mo le faʻaulufaleina mai i le 2005, e sili atu i le 100 kamupani faʻatau oloa i totonu o le atunuʻu ua talosaga mo le resitalaina o le oloa;faatasi ai ma i latou, o le kamupani gaosiga faamaonia e aofia ai Jiangsu Zhengda Tianqing Pharmaceutical (muamua faafoliga), Hainan Zhonghe Pharmaceutical, ma Fujian Guangxi Pharmaceutical Co., Ltd. Shengtang Pharmaceutical, Jiangxi Qingfeng Pharmaceutical, Suzhou Dawnrays Pharmaceutical, Shanghai Qingsong Pharmaceutical, Sichuan Haiscoutical Pharmaceutical, Sichuan Haiscoutical. Lukang, Zhejiang Huasheng Biopharmaceutical, Changzhi Sanbao Biochemical.

Pharmaceutical, Anhui Baker Biopharmaceutical, Hunan Concord Pharmaceutical Industry, Beijing Xiehe Pharmaceutical Factory, Beijing Baiao Pharmaceutical, Xinlitai Pharmaceutical, Dongyangguang, ma isi;mai le aso o le konekarate, o lenei oloa ua ulufale atu i tulaga o lauiloa lauiloa ituaiga talu mai le 2007.

Matou te tuʻuina atu foʻi kamupani faʻatau oloa poʻo auaunaga ma kamupani faʻamalosia vaalele.E iai a matou lava fale gaosimea ma ofisa su'esu'e.E mafai ona faigofie ona matou tuʻuina atu ia te oe toetoe lava o ituaiga uma o oloa e tutusa ma a matou oloa eseese mo PriceList mo le High Quality Antiviral Entecavir Powder CAS 142217-69-4 ma le Tau Sili, O le a matou taumafai pea e faʻateleina la matou kamupani ma tuʻuina atu oloa sili ona lelei. fa'atasi ai ma tau fa'atauva'a.So'o se su'esu'ega po'o se fa'amatalaga e matua fa'afetaia.Manatua e pu'e fua mai ia i matou.
PriceList moSaina Entecavir ma 142217-69-4, Matou te faʻafeiloaʻi ma le fiafia tagata faʻatau i totonu ma fafo e asiasi i la matou kamupani ma fai se talanoaga faʻapisinisi.O la matou kamupani e faʻamalosia pea le mataupu faavae o le "lelei lelei, tau talafeagai, le auaunaga muamua-vasega".Matou te naunau e fausia se taimi umi, faauo ma felagolagomai faʻatasi ma oe.