Fa'atau A'oa'o Si'isi'i Fa'atauina vevela Ibrutinib Intermediates N-3 CAS 330792-70-6

Faatasi ai ma lenei mautauave i le mafaufau, ua avea nei i matou ma se tasi e foliga mai e sili atu ona fou tekinolosi, taugofie, ma tau-faatauva gaosi oloa mo Wholesale Hot Selling Ibrutinib Intermediates N-3 CAS 330792-70-6, Matou te tulimatai atu e tuʻuina atu ia te oe a matou oloa i se taimi lata mai, ma o le a e mauaina la matou upusii e matua talafeagai ma le lelei oa matou oloa e sili ona lelei!
Faatasi ai ma lenei mautauave i le mafaufau, ua avea nei i matou ma se tasi e foliga mai e sili ona faʻatekonolosi fou, taugofie, ma tau-faatauva gaosi oloa mo.Saina Ibrutinib N-3 ma Intermediates, E oʻo mai i le taimi nei ua faʻatau atu a matou oloa i Europa i sasaʻe, Sasaʻe Tutotonu, Sautesasae, Aferika ma Amerika i Saute ma isi. E 13years faʻatauga faʻapolofesa ma faʻatau i vaega Isuzu i le fale ma fafo ma le umiaina o faiga faʻaonaponei eletise Isuzu siaki.Matou te faʻaaloalo i le matou pule autu o le Faʻamaoni i pisinisi, faʻamuamua i le tautua ma o le a matou faia le mea sili matou te mafaia e ofoina atu i matou tagata faʻatau oloa maualuga ma auaunaga sili ona lelei.

Fa'asao mo le tu'ufa'atasiga o le allopurinol.

O se tasi lea o le 3-amino-4-substituted pyrazole series.E mafai ona faʻaaogaina e avea o se vaeluagalemu e faʻapipiʻi ai le tele o vailaʻau faʻapitoa faʻapitoa, e pei o le allopurinol, o se tasi o le pyrazolopyrimidine derivatives series, o le mulimuli talu mai le 1963 Talu mai lona faʻaogaina i le falemaʻi, o le vailaʻau autu mo le togafitiga o le gout.I le taimi nei, e itiiti lava auala iloa mo le faʻapipiʻiina

3-aminopyrazole-4-carboxamide hemisulfate i Saina, e masani lava e ala i le tali malononitrile ma triethyl orthoformate e saunia ethoxymethylene malononitrile, ona sosoo ai lea ma le O le tali atu o le hydrazine hydrate e maua ai le 3-amino-4-cyanopyrazole, lea e iu lava ina faʻafefeteina ma le faʻamaʻi faʻamaʻi e maua ai le faʻamaʻi faʻamaʻi.

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), o le aofaʻi o fua o le faʻapipiʻi e ala i lenei metotia e tusa ma le 60% (faʻatusatusaina o le malononitrile), o lenei metotia E aofia ai se tali e tolu-laasaga, o laʻasaga e umi, ma o mea faʻaaogaina, e pei o le malononitrile ma le ethoxymethylene malononitrile, e sili atu ona oona ma taugata.E le gata i lea, o le 3-aminopyrazole-4 ua saunia e lenei metotia -Formamide hemisulfate o loʻo i ai se lanu e faigata ona aveese ma manaʻomia ai le faʻaogaina atili, lea e sili atu ona faigata.

O loʻo i ai lipoti i tusitusiga mai fafo e faʻaaoga ai le pyridylamide hydrazone ma le ethoxymethylene malononitrile e avea ma mea mataʻutia e maua ai le 3-amino-4-cyanopyrazole e ala i le faʻaopoopoga ma le cyclization, ona tali atu lea i le sulfuric acid concentrated e maua ai le faʻapipiʻi sini (Reuken G Jones. Reactions of orthoesters with activemethylene compounds [J] J Am Chem Soc. 1952,74(5):4889 4891).O mea autu autu o loʻo faʻaaogaina i lenei metotia e taugata, o le gaioiga o le gaioiga e le maualuga, ma o le tupe mama o le gaosiga o pisinisi e maualalo.E tatau ona faigata.

Tulaga Fa'atonu:Enterprise Standard
fafo:pa'epa'e pa'epa'e po'o samasama pauta

afifi:25kg/papa
su'ega (HPLC) mea e sili atu pe tutusa ile 98.0%
mama （HPLC） mea e sili atu pe tutusa ile 99.5%

JIN DUN Medical uaFa'ailoga ISO ma fa'amalieina tulaga fa'atupu GMP, fa'afaigaluegaina tagata tomai faapitoa i le fa'aogaina o vaila'au i totonu ma fafo ma le poto masani e ta'ita'ia le R&D a le kamupani.

FA'ATAITAI O GALUEGA
●Mata'u maualuga Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Toe Fa'atonuga
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction

Meafaigaluega

O loʻo i ai i la matou Fale suʻesuʻe mea faʻapitoa ma suʻega, e pei o le: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope…

Vaega su'esu'e

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Ua matou fesoasoani i nisi o kamupani pito i luga ole fale talavai, pei oleHansoh, Hengrui ma HEC Pharm.O iinei o le a tatou faaali atu ai se vaega o latou.

Fa'asinomaga Tulaga Muamua:

Kase Numera: 110351-94-5

Tulaga Fa'apitoa Lua:

Cas Nu.: 144848-24-8

Tulaga Fa'apitoa Tolu:

Cas Nu.: 200636-54-0

1.Fa'asinomaga Fou Intermediates po'o API.E tutusa ma le faʻasoaina o mataupu i luga, o loʻo i ai i tagata faʻatau manaʻoga mo Intermediates patino poʻo API, ma e le mafai ona latou mauaina oloa manaʻomia i le maketi, ona mafai lea ona matou fesoasoani i le Customize.

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Faatasi ai ma lenei mautauave i le mafaufau, ua avea nei i matou ma se tasi e foliga mai e sili atu ona fou tekinolosi, taugofie, ma tau-faatauva gaosi oloa mo Wholesale Hot Selling Ibrutinib Intermediates N-3 CAS 330792-70-6, Matou te tulimatai atu e tuʻuina atu ia te oe a matou oloa i se taimi lata mai, ma o le a e mauaina la matou upusii e matua talafeagai ma le lelei oa matou oloa e sili ona lelei!
Fa'atau atuSaina Ibrutinib N-3 ma Intermediates, E oʻo mai i le taimi nei ua faʻatau atu a matou oloa i Europa i sasaʻe, Sasaʻe Tutotonu, Sautesasae, Aferika ma Amerika i Saute ma isi. E 13years faʻatauga faʻapolofesa ma faʻatau i vaega Isuzu i le fale ma fafo ma le umiaina o faiga faʻaonaponei eletise Isuzu siaki.Matou te faʻaaloalo i le matou pule autu o le Faʻamaoni i pisinisi, faʻamuamua i le tautua ma o le a matou faia le mea sili matou te mafaia e ofoina atu i matou tagata faʻatau oloa maualuga ma auaunaga sili ona lelei.