4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin;
4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin;
E galue e ala i le faaosofia o le presynaptic tutotonu alpha 2- talitali.O lona a'afiaga e pei o le nifedipine, o le calcium antagonist, ma le captopril, o le ACE inhibitor.Mo le maualuga maualuga.
O lenei oloa e tatau ona faʻaaogaina le faʻavae o vailaʻau faʻapitoa.E masani ona amata mai le fua maualalo, o lona uiga, 0.2mg, tasi i le aso, inu i le taeao.E tatau ona fai fetuutuunaiga o fualaau i le tolu vaiaso se'ia maua i'uga lelei.Ole fua masani ole 0.2mg tasi, faalua ile aso (taeao ma afiafi).Ole maualuga ole fua ile taimi e le tatau ona sili atu ile 0.4mg, ma ole maualuga ole fua ole aso ole a le sili atu ile 0.6mg.Mo tagata mamaʻi e mama pe feololo le le atoatoa o le fatu, o le fua e tasi e le tatau ona sili atu i le 0.2 mg poʻo le fua o le aso e le tatau ona sili atu i le 0.4 mg.
O lenei oloa o le α2-receptor agonist, lea o se vailaʻau faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi.Fa'aaogaina mo le maualuga ma le ogaoga tulaga muamua ma le maualuga maualuga.
Talu ai e taofia ai le fa'alilo ma le fegasoloa'i o le gastrointestinal tract, e talafeagai foi mo tagata mama'i toto o lo'o maua i le ma'i papala.O le tuufaatasiga o lenei vailaʻau ma diuretics e mafai ona faʻaleleia atili ai le aoga.Ose vaila'au fa'amalosi fa'atotonugalemu ma se vaila'au fa'ama'i fa'amalosi laina lona lua.E masani lava ona fa'atinoina i le lotoifale ile ophthalmology.O lenei oloa ei ai le aafiaga o le faʻaitiitia o le mamafa o le intraocular, ma e le afaina ai le tamaititi ma le faʻaogaina o mata.E mafai ona faʻapipiʻi toto toto i le mata, faʻaitiitia le gaosiga o le malie aqueous, ma ausia le aʻafiaga o le faʻaitiitia o le mamafa o le intraocular.E amata ona aoga ile 15 minute pe a uma le mata ma e mafai ona faatumauina le aafiaga mo le 8 itula.
Tulaga:EP10
Su'ega mea:97.5-102.0%
fafo:Pa'epa'e pe toetoe a pei o le pauta
afifi:1kg / taga poʻo e manaʻomia e tagata faʻatau
JIN DUN Medical uaFa'ailoga ISO ma fa'amalieina tulaga fa'atupu GMP, fa'afaigaluegaina tagata tomai faapitoa i le fa'aogaina o vaila'au i totonu ma fafo ma le poto masani e ta'ita'ia le R&D a le kamupani.
FA'ATAITAI O GALUEGA
●Mata'u maualuga Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction .Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Toe Fa'atonuga
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Gignard Reaction
Meafaigaluega
O loʻo i ai i la matou Fale suʻesuʻe mea faʻapitoa ma suʻega, e pei o le: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
Vaega su'esu'e
Jindun Medical ei ai se vaega o tagata faigaluega R & D faʻapolofesa, ma faʻafaigaluegaina le tele o tagata tomai faʻapitoa mo vailaʻau faʻapitoa i totonu ma fafo e taʻitaʻia le R&D, ma faʻafaigofie atili ma lelei a tatou faʻasologa.
Ua matou fesoasoani i nisi o kamupani pito i luga ole fale talavai, pei oleHansoh, Hengrui ma HEC Pharm.O iinei o le a tatou faaali atu ai se vaega o latou.
Fa'asinomaga Tulaga Muamua:
Kase Numera: 110351-94-5
Tulaga Fa'apitoa Lua:
Cas Nu.: 144848-24-8
Tulaga Fa'apitoa Tolu:
Cas Nu.: 200636-54-0
1.Fa'asinomaga Fou Intermediates po'o API.E tutusa ma le faʻasoaina o mataupu i luga, o loʻo i ai i tagata faʻatau manaʻoga mo Intermediates patino poʻo API, ma e le mafai ona latou mauaina oloa manaʻomia i le maketi, ona mafai lea ona matou fesoasoani i le Customize.
2.Fa'atonuga Fa'agasologa mo Oloa Tuai.O la matou 'au o le a fesoasoani i le fa'aleleia ma le fa'aleleia o ia gaosiga o lo'o tuai ai le auala e tali mai ai, e maualuga le tau o gaosiga, ma e maualalo le lelei.E mafai ona matou tuʻuina atu faʻamaumauga atoa mo le faʻaaogaina o tekonolosi ma le faʻaleleia atili o le faagasologa, fesoasoani i tagata faʻatau mo se gaosiga sili atu.
Mai fuala'au fa'atatau ile INDs, JIN DUN Medical e tu'uina atu ia te oefofo R&D fa'apitoa e tasi taofi.
JIN DUN Fomaʻi faʻamalosi i le fatuina o se 'au ma miti, faia o oloa mamalu, faʻaeteete, malosi, ma alu uma e avea ma paaga faʻalagolago ma uo a tagata faʻatau!
